Invitrogen™ Stargazin Monoclonal Antibody (N245/36)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527645

Catalog No. PIMA527645

Description

1 μg/mL of MA5-27645 was sufficient for detection of TARP Gamma2/4/8 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 35-55kDa. Does not cross-react with TARPGamma3. This antibody was formerly sold as clone S245-36.

Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors.

Specifications

• Antigen: Stargazin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
• Gene Accession No.: O88602, Q71RJ2, Q9Y698
• Gene Symbols: Cacng2
• Immunogen: Fusion protein amino acids 203-323 (Cytoplasmic C-terminus) of rat TARPGamma2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Western Blot, Immunocytochemistry
• Clone: N245/36
• Conjugate: Unconjugated
• Gene: Cacng2
• Gene Alias: AW060990; B230105C07Rik; B930041E13Rik; CACNG2; calcium channel, voltage-dependent, gamma subunit 2; calcium voltage-gated channel auxiliary subunit gamma 2; CaV gamma 2; Ipr328; MGC123981; MGC138502; MGC138504; MRD10; Neuronal voltage-gated calcium channel gamma-2 subunit; stargazer; Stargazin; stg; TARP; TARP gamma 2; TARP gamma-2; Transmembrane AMPAR regulatory protein gamma-2; voltage-dependent calcium channel gamma-2 subunit; voltage-dependent calcium channel subunit gamma; wag; waggler
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 10369, 12300, 84347
• Content And Storage: -20°C
• Form: Liquid