Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
STAT1 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A302753AT
Description
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Pig
STAT1 (signal transducers and activators of transcription 1) is a member of the STAT family of transcription factors. STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6. STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism. Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure. The STAT1 gene is located on chromosome 2. STAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus to regulate transcription of many different genes. Among the seven STATs types, STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile. STAT1 is activated by many different ligands including IFN family (IFN-Alpha, IFN-Beta, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1). Two alternatively spliced transcript variants encoding distinct isoforms of STAT1 have been described.Specifications
| STAT1 | |
| Polyclonal | |
| TBS with 0.1% BSA and 0.09% sodium azide | |
| P42224, P42225 | |
| Stat1 | |
| Between 700 and 750 | |
| 20 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| Western Blot | |
| Unconjugated | |
| STAT1 | |
| DKFZp686B04100, ISGF-3, STAT91 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 20846, 6772 | |
| 4° C | |
| Liquid |
Provide Content Correction
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.
Product Title