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Invitrogen™ STAT2 Recombinant Rabbit Monoclonal Antibody (JF0884)
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Catalog No. PIMA542463
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100 μL
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PIMA542463 100 μL
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Catalog No. PIMA542463 Supplier Invitrogen™ Supplier No. MA542463
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: A431, A549, SW480, human lung cancer tissue, human colon cancer tissue, mouse skin tissue. Subcellular Location: Cytoplasm, Nucleus.

STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STAT2
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone JF0884
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Stat2
Gene Accession No. P52630, Q9WVL2
Gene Alias 1110034C02Rik; 1600010G07Rik; acute phase response factor; acute-phase response factor; ADMIO; ADMIO1; Aprf; AW109958; AW496480; DNA-binding protein APRF; EGK_03803; HIES; IMD44; interferon alpha induced transcriptional activator; ISGF-3; MGC59816; p113; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kDa; signal transducer and activator of transcription 3; signal transducer and activator of transcription 3 (acute-phase response factor); STAT; STAT 2; STAT113; STAT2; STAT-2; Stat3
Gene Symbols Stat2
Host Species Rabbit
Immunogen Synthetic peptide within human stat2 aa 1-49.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20847, 288774, 6773
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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