Invitrogen™ STAT5 alpha/beta Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ 44368G

Catalog No. 44-368-G

Description

STAT5 alpha/beta Polyclonal Antibody for Western Blot, ICC/IF

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of, many cell ligands, such as IL-2, IL-3, IL-7, GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/ BCL-X(L), which suggests the antiapoptotic function of this gene in cells.

Specifications

• Antigen: STAT5 alpha/beta
• Classification: Polyclonal
• Formulation: Dulbecco's PBS with 1mg/mL BSA and 0.05% sodium azide; pH 7.3
• Gene Accession No.: P42229, P42230, P42232, P51692, P52632, Q62771
• Gene Symbols: STAT5A, STAT5B
• Immunogen: The antiserum was produced against a chemically synthesized peptide derived from an internal region of human STAT 5. The sequence is conserved in human, mouse and rat.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Gene: STAT5A
• Gene Alias: AA959963; Mammary gland factor; mammary gland factor STAT5A; mammary gland factor STAT5B; mammary gland factor; transcription factor; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5a; Signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; Stat5a; Stat5b; transcription factor STAT5B
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20850, 20851, 24918, 25126, 6776, 6777
• Content And Storage: -20°C
• Form: Liquid