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Invitrogen™ STAT5 beta Polyclonal Antibody

Catalog No. PIPA5121574
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200 μL
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PIPA5121574 20 μL
PIPA5119418 200 μL
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Catalog No. PIPA5121574 Supplier Invitrogen™ Supplier No. PA5121574
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Description

Rabbit Polyclonal Antibody

STAT5 beta Polyclonal Antibody for Western Blot, ICC/IF

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STAT5 beta
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
Gene Stat5b
Gene Accession No. P51692
Gene Alias LOC101122961; mammary gland factor STAT5B; Signal transducer and activator of transcription 5a; signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; STAT5B; transcription factor STAT5B
Gene Symbols Stat5b
Host Species Rabbit
Immunogen Recombinant protein Signal Transducer And Activator Of Transcription 5B. The antigen corresponds to amino acid range 497-749 of the target protein.
Purification Method Antigen affinity chromatography, Protein A
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6777
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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