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Invitrogen™ STAT5 beta Polyclonal Antibody
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Catalog No. 712500
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Catalog No. Quantity
71-250-0 100 μg
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Catalog No. 71-250-0 Supplier Invitrogen™ Supplier No. 712500
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Description

Rabbit Polyclonal Antibody

STAT5 beta Polyclonal Antibody for ChIP, ELISA, EMSA, IHC (P), IP, Western Blot

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STAT5 beta
Applications ChIP Assay, ELISA, Gel Shift, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene Stat5b
Gene Accession No. P42232, P51692, P52632
Gene Alias LOC101122961; mammary gland factor STAT5B; Signal transducer and activator of transcription 5a; signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; STAT5B; transcription factor STAT5B
Gene Symbols Stat5b
Host Species Rabbit
Immunogen Peptide corresponding to the C-terminus of murine Stat5b coupled to protein carrier.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20851, 25126, 6777
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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