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  6. Invitrogen™ STAT5 beta Recombinant Rabbit Monoclonal Antibody (BLR146J)

Invitrogen™ STAT5 beta Recombinant Rabbit Monoclonal Antibody (BLR146J)

Catalog No. PIMA544480
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PIMA544480 10 μL
PIMA544479 100 μL
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Catalog No. PIMA544480 Supplier Invitrogen™ Supplier No. MA544480
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Description

Rabbit Recombinant Monoclonal Antibody

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STAT5 beta
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone BLR146J
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation BBS with 0.09% sodium azide; pH 8.2
Gene Stat5b
Gene Accession No. P51692
Gene Alias LOC101122961; mammary gland factor STAT5B; Signal transducer and activator of transcription 5a; signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; STAT5B; transcription factor STAT5B
Gene Symbols Stat5b
Host Species Rabbit
Immunogen Peptide representing a region between residue 737 and the C-terminus (residue 787) of Human Signal Transducer and Activator of Transcription 5B.
Purification Method purified
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6777
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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