STAT6 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA587502

Catalog No. PIPA587502

Description

Positive Samples: HeLa, Jurkat, A-431, THP-1; Cellular Location: Cytoplasm, Nucleus Immunogen sequence: AACTCCTGCT AATGGGACTG GGCCAAGTGA GGCCCTGGCC ATGCTACTGC AGGAGACCAC TGGAGAGCTA GAGGCAGCCA AAGCCCTAGT GCTGAAGAGG

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.

Specifications

• Antigen: STAT6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STAT6
• Gene Alias: 12S1644, D12S1644, IL4 STAT, IL-4 Stat, IL-4-STAT, signal transducer and activator of transcription 6, signal transducer and activator of transcription 6, interleukin-4 induced, signal transducer and transcription activator 6, STAT, STAT, interleukin4-induced, Stat6, STAT-6, STAT6B, STAT6C, transcription factor IL-4 STAT
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20852, 362896, 6778
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Western Blot
• Concentration: 2.07 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
• Gene Accession No.: P42226, P52633
• Gene Symbols: STAT6
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 501-600 of human STAT6 (NP_0031443)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG