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Invitrogen™ STAT6 Recombinant Rabbit Monoclonal Antibody (SY13-09)
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Catalog No. PIMA542422
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100 μL
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Catalog No. Quantity
PIMA542422 100 μL
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Catalog No. PIMA542422 Supplier Invitrogen™ Supplier No. MA542422
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: NIH/3T3 cell lysate, Hela cell lysate, Raji cell lysate, Daudi cell lysate, Hela, HepG2, NIH/3T3, mouse lung tissue, human kidney tissue. Subcellular Location: Cytoplasm, Nucleus.

STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL13. (Stat6-/-) were found to be deficient in IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4 mediated proliferation. STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response. STAT6 is crucial for IL-4-mediated biological responses, and naturally in two isoforms: STAT6a and STAT6c.
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Specifications

Antigen STAT6
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone SY13-09
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene STAT6
Gene Accession No. P42226, P52633
Gene Alias 12S1644; D12S1644; IL4 STAT; IL-4 Stat; IL-4-STAT; signal transducer and activator of transcription 6; signal transducer and activator of transcription 6, interleukin-4 induced; signal transducer and transcription activator 6; STAT; STAT, interleukin4-induced; Stat6; STAT-6; STAT6B; STAT6C; transcription factor IL-4 STAT
Gene Symbols STAT6
Host Species Rabbit
Immunogen Synthetic peptide within human stat6 c terminal.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20852, 6778
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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