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Staufen Mouse anti-Human, Clone: OTI5F6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527478

Catalog No. PIMA527478


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Description

Description

Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5 ft.UTR.
Specifications

Specifications

Staufen
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
O95793
RP3-470L14.2, STAU; double-stranded RNA-binding protein Staufen homolog 1
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
6780
Western Blot
OTI5F6
Unconjugated
STAU1
Liquid
STAU1
Full length human recombit protein of STAU1 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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