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Staufen1 Rabbit anti-Human, Mouse, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A303956A

Description
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Panda
Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5′UTR.Specifications
Staufen1 | |
Polyclonal | |
Unconjugated | |
STAU1 | |
RP3-470L14.2, STAU; double-stranded RNA-binding protein Staufen homolog 1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
20853, 6780 | |
4° C | |
Liquid |
Immunoprecipitation, Western Blot | |
1 mg/ml | |
phosphate, tris citrate with 0.09% sodium azide; pH 7-8 | |
O95793, Q9Z108 | |
STAU1 | |
Between 1 and 50 | |
100 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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