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Invitrogen™ STEAP3 Polyclonal Antibody
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Catalog No. PIPA530676
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100 μL
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PIPA530676 100 μL
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Catalog No. PIPA530676 Supplier Invitrogen™ Supplier No. PA530676
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Rabbit Polyclonal Antibody

Recommended positive controls: HepG2 cytoplasm extract. Predicted reactivity: Mouse (89%), Rat (87%), Bovine (86%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STEAP3
Applications Western Blot
Classification Polyclonal
Concentration 1.79 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene STEAP3
Gene Accession No. Q658P3
Gene Alias 1010001D01Rik; AHMIO2; dudlin 2; dudlin-2; dudulin 2; dudulin-2; hpHyde; hTSAP6; Metalloreductase STEAP3; pHyde; Protein nm1054; six-transmembrane epithelial antigen of prostate 3; STEAP family member 3; STEAP family member 3, metalloreductase; STEAP3; STEAP3 metalloreductase; STMP3; TSAP6; tumor suppressor pHyde; tumor suppressor-activated pathway protein 6
Gene Symbols STEAP3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human STEAP3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55240
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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