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Invitrogen™ STEAP3 Polyclonal Antibody
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Catalog No. PIPA587478
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100 μL
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PIPA587478 100 μL
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Catalog No. PIPA587478 Supplier Invitrogen™ Supplier No. PA587478
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MPEEMDKPLI SLHLVDSDSS LAKVPDEAPK VGILGSGDFA RSLATRLVGS GFKVVVGSRN PKRTARLFPS AAQVTFQEEA VSSPEVIFVA VFREHYSSLC SLSDQLAGKI LVDVSNPTEQ EHLQHRESNA EYLASLFPTC TVVKAFNVIS AWTLQAGPRD GNRQVPICGD QPEAKRAVSE; Positive Samples: Mouse heart; Cellular Location: Endosome membrane, Multi-pass membrane protein.

The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STEAP3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene STEAP3
Gene Accession No. Q8CI59
Gene Alias 1010001D01Rik; AHMIO2; dudlin 2; dudlin-2; dudulin 2; dudulin-2; hpHyde; hTSAP6; Metalloreductase STEAP3; pHyde; Protein nm1054; six-transmembrane epithelial antigen of prostate 3; STEAP family member 3; STEAP family member 3, metalloreductase; STEAP3; STEAP3 metalloreductase; STMP3; TSAP6; tumor suppressor pHyde; tumor suppressor-activated pathway protein 6
Gene Symbols STEAP3
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 68428
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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