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Invitrogen™ STEAP3 Polyclonal Antibody
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Catalog No. PIPA5115970
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100 μL
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PIPA5115970 100 μL
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Catalog No. PIPA5115970 Supplier Invitrogen™ Supplier No. PA5115970
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total STEA3.

The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STEAP3
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene STEAP3
Gene Accession No. Q5RKL5, Q658P3, Q8CI59
Gene Alias 1010001D01Rik; AHMIO2; dudlin 2; dudlin-2; dudulin 2; dudulin-2; hpHyde; hTSAP6; Metalloreductase STEAP3; pHyde; Protein nm1054; six-transmembrane epithelial antigen of prostate 3; STEAP family member 3; STEAP family member 3, metalloreductase; STEAP3; STEAP3 metalloreductase; STMP3; TSAP6; tumor suppressor pHyde; tumor suppressor-activated pathway protein 6
Gene Symbols STEAP3
Host Species Rabbit
Immunogen A synthesized peptide derived from human STEAP3(Accession Q658P3), corresponding to amino acid residues D16-R66.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170824, 55240, 68428
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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