Invitrogen™ STEAP4 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA518782

Catalog No. PIPA518782

Description

This antibody is predicted to react with canine, mouse and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 4,000.

The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.

Specifications

• Antigen: STEAP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STEAP4
• Gene Alias: 1110021O17Rik; Ab1-219; AI481214; DKFZp666D049; dudulin 4; dudulin-4; FLJ23153; Metalloreductase STEAP4; six transmembrane prostate protein 2; six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STAMP2; STEAP family member 4; STEAP4; STEAP4 metalloreductase; TIARP; Tnfa-induced adipose-related protein; Tnfaip9; Tumor necrosis factor, alpha-induced protein 9; tumor necrosis factor-alpha-induced adipose-related protein; tumor necrosis-alpha-induced adipose-related protein
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 79689
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q687X5
• Gene Symbols: STEAP4
• Immunogen: Synthetic peptide sequence (CVDNTLTRIRQGWERN) corresponding to the C-terminus amino acids of STEAP4 (aa 441-457).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG