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Invitrogen™ STEAP4 Polyclonal Antibody
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Catalog No. PIPA5106509
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100 μL
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PIPA5106509 100 μL
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Catalog No. PIPA5106509 Supplier Invitrogen™ Supplier No. PA5106509
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total STEAP4.

The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STEAP4
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene STEAP4
Gene Accession No. Q687X5, Q923B6
Gene Alias 1110021O17Rik; Ab1-219; AI481214; DKFZp666D049; dudulin 4; dudulin-4; FLJ23153; Metalloreductase STEAP4; six transmembrane prostate protein 2; six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STAMP2; STEAP family member 4; STEAP4; STEAP4 metalloreductase; TIARP; Tnfa-induced adipose-related protein; Tnfaip9; Tumor necrosis factor, alpha-induced protein 9; tumor necrosis factor-alpha-induced adipose-related protein; tumor necrosis-alpha-induced adipose-related protein
Gene Symbols STEAP4
Host Species Rabbit
Immunogen A synthesized peptide derived from human STEAP4(Accession Q687X5), corresponding to amino acid residues L422-H459.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117167, 79689
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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