Invitrogen™ STEAP4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106509

Catalog No. PIPA5106509

Description

Antibody detects endogenous levels of total STEAP4.

The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression.

Specifications

• Antigen: STEAP4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STEAP4
• Gene Alias: 1110021O17Rik; Ab1-219; AI481214; DKFZp666D049; dudulin 4; dudulin-4; FLJ23153; Metalloreductase STEAP4; six transmembrane prostate protein 2; six-transmembrane epithelial antigen of prostate 4; SixTransMembrane protein of prostate 2; STAMP2; STEAP family member 4; STEAP4; STEAP4 metalloreductase; TIARP; Tnfa-induced adipose-related protein; Tnfaip9; Tumor necrosis factor, alpha-induced protein 9; tumor necrosis factor-alpha-induced adipose-related protein; tumor necrosis-alpha-induced adipose-related protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117167, 79689
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q687X5, Q923B6
• Gene Symbols: STEAP4
• Immunogen: A synthesized peptide derived from human STEAP4(Accession Q687X5), corresponding to amino acid residues L422-H459.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG