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STF 118804
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Quantity:
5 mg
25 mg
Description
STF 118804 is a NAMPT inhibitor (nicotinamide phosphoribosyltransferase, visfatin, PBEF1); inhibits NAD+ synthesis from nicotinamide. Potently inhibits the viability of multiple B-cell acute lymphoplastic leukemia (B-ALL) cell lines (IC50 < 10 nM); induces apoptosis in MF-411 cells. Induces regression of ALL xenografts and eliminates leukemia stems cells from bone marrow in mice.
Specifications
Specifications
Chemical Name or Material | 4-[5-Methyl-4-[[(4-methylphenyl)sulfonyl]methyl]-2-oxazolyl]-N-(3-pyridinylmethyl)benzamide |
CAS | 894187-61-2 |
Assay Percent Range | >98% |
Quantity | 25 mg |
Molecular Formula | C25H23N3O4S |
Formula Weight | Observed MW: 461.53 |
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