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Invitrogen™ STIM2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA517146
Description
It is not recommended to aliquot this antibody.
In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist.
Specifications
STIM2 | |
Polyclonal | |
0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5 | |
P83093, Q9P246 | |
STIM2 | |
Synthetic peptide corresponding to the sequence of human STIM2. | |
100 μL | |
Primary | |
Human, Mouse, Rat, Monkey | |
Antibody | |
IgG |
Western Blot, Immunocytochemistry | |
Unconjugated | |
STIM2 | |
Kiaa1482; OTTHUMP00000123457; OTTHUMP00000123458; OTTHUMP00000216198; Stim2; Stromal interaction molecule 2 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
116873, 117087, 57620 | |
-20°C | |
Liquid |
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