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Invitrogen™ STING Monoclonal Antibody (OTI4E12)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA526032

Catalog No. PIMA526032


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Description

Description

STING Monoclonal Antibody for Western Blot, ICC/IF, IHC (P)

STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. STING may have translocon function, the translocon possibly being able to influence the induction of type I interferons and is also involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II) thus facilitating the detection of intracellular viral RNA species as well as B-form DNA and mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. Generally seen in endoplasmic reticulum membrane, cell membrane and mitochondrion outer membrane, it is ubiquitously expressed in most of tissues.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

STING
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q86WV6
TMEM173
Full length human recombinant protein of TMEM173 produced in HEK293T cell.
100 μL
Primary
Human
Antibody
IgG2a
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
OTI4E12
Unconjugated
TMEM173
2610307O08Rik; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; ERIS; hMITA; hSTING; hypothetical LOC533661; mediator of IRF3 activation; Mita; mitochondrial mediator of IRF3 activation; mitochondrial transmembrane protein 173; MMITA; Mpys; mSTING; NET23; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; poSTING; RGD1562552; rSTING; SAVI; Stimulator of interferon genes protein; stimulator of interferon response cGAMP interactor 1; STING; STING1; tm173; Tmem173; Transmembrane protein 173
Mouse
Affinity Chromatography
RUO
340061
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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