STK11 Monoclonal Antibody (OTI1F10), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA802377

Catalog No. 50-167-9218

Description

LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11), a member of the serine/threonine kinase family, is a tumor suppressor. LKB1 physically associates with p53 and regulates specific p53 dependent apoptosis pathways. LKB1 is present in both the cytoplasm and nucleus of living cells and translocates to mitochondria during apoptosis. LKB1 functions as a master upstream protein kinase, regulating AMPK related kinases as well as AMPK. Mutations in LKB1 gene are associated with Peutz Jeghers syndrome.

Specifications

• Antigen: STK11
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q15831
• Gene Symbols: STK11
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-236 of human STK11 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1F10
• Conjugate: Unconjugated
• Gene: STK11
• Gene Alias: LKB1, PJS, hLKB1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6794
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid