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Invitrogen™ STK25 Polyclonal Antibody
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Catalog No. PIPA569552
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100 μL
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PIPA569552 100 μL
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Catalog No. PIPA569552 Supplier Invitrogen™ Supplier No. PA569552
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rat: 100%.

STK25 (YSK1) is a serine/threonine kinase that belongs to the GCK family of kinases. It has been implicated as an upstream regulator of MAP kinase signaling pathways. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STK25
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene STK25
Gene Accession No. 0
Gene Alias 1500019J11Rik; AU018434; C86992; hypothetical protein; serine/threonine kinase 25; serine/threonine kinase 25 (STE20 homolog, yeast); serine/threonine kinase 25 (Ste20, yeast homolog); serine/threonine kinase 25 (yeast); serine/threonine-protein kinase 25; SOK1; SOK-1; Ste20, yeast homolog; ste20/oxidant stress response kinase 1; Ste20-like; ste20-like kinase; sterile 20/oxidant stress-response kinase 1; STK25; STK25 protein; Yeast Sps1/Ste20-related kinase 1; Ysk1
Gene Symbols STK25
Host Species Rabbit
Immunogen synthetic peptide corresponding to a region of rat STK25.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 373542
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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