Invitrogen™ STK38 Polyclonal Antibody

Catalog No.	Quantity
PIPA537923	100 μg

Catalog No. PIPA537923 Supplier Invitrogen™ Supplier No. PA537923

Description

Goat Polyclonal Antibody

This antibody is predicted to react with dog, pig and cow based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

STK38 (also known as NDR) or Nuclear Dbf2-related protein is a serine/threonine kinase in the subgroup of the AGC kinase family that is regulated by Mob proteins. Fas and TNFα receptor stimulation activates human STK38 by promoting phosphorylation at the hydrophobic motif. NDR acts as a novel pro-apoptotic kinase, and is a key member of the RASSF1A/MST1 signaling cascade. STK38 is crucial for the fidelity of mitotic chromosome alignment in mammalian cells. STK38 is incorporated into the HIV-1 particles and is cleaved by the HIV-1 protease. STK38-driven centrosome duplication requires Cdk2 activity, and Cdk2-induced centrosome amplification is affected upon reduction of STK38 activity.

Specifications

• Antigen: STK38
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene: STK38
• Gene Accession No.: Q15208
• Gene Alias: 5830476G13Rik; 9530097A09Rik; AA617404; NDR; Ndr Ser/Thr kinase-like protein; NDR1; NDR1 protein kinase; nuclear Dbf2-related kinase 1; serine/threonine kinase 38; serine/threonine-protein kinase 38; STK38
• Gene Symbols: STK38
• Host Species: Goat
• Immunogen: Peptide with sequence C-KPTVATSNHPET, from the C-terminus of STK38 (aa 420-431).
• Purification Method: Ammonium sulfate precipitation
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 11329, 361813
• Target Species: Human, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

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