Invitrogen™ STK38 Polyclonal Antibody

Catalog No.	Quantity
PIPA5110442	100 μL

Catalog No. PIPA5110442 Supplier Invitrogen™ Supplier No. PA5110442

Description

Rabbit Polyclonal Antibody

Immunogen sequence: ILKPTVATSN HPETDYKN.

STK38 (also known as NDR) or Nuclear Dbf2-related protein is a serine/threonine kinase in the subgroup of the AGC kinase family that is regulated by Mob proteins. Fas and TNFα receptor stimulation activates human STK38 by promoting phosphorylation at the hydrophobic motif. NDR acts as a novel pro-apoptotic kinase, and is a key member of the RASSF1A/MST1 signaling cascade. STK38 is crucial for the fidelity of mitotic chromosome alignment in mammalian cells. STK38 is incorporated into the HIV-1 particles and is cleaved by the HIV-1 protease. STK38-driven centrosome duplication requires Cdk2 activity, and Cdk2-induced centrosome amplification is affected upon reduction of STK38 activity.

Specifications

• Antigen: STK38
• Applications: ELISA, Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.42 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene: STK38
• Gene Accession No.: Q15208, Q91VJ4
• Gene Alias: 5830476G13Rik; 9530097A09Rik; AA617404; NDR; Ndr Ser/Thr kinase-like protein; NDR1; NDR1 protein kinase; nuclear Dbf2-related kinase 1; serine/threonine kinase 38; serine/threonine-protein kinase 38; STK38
• Gene Symbols: STK38
• Host Species: Rabbit
• Immunogen: Synthetic peptide
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 106504, 11329
• Target Species: Human, Mouse
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG