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STK38 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987160
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50-198-7160 100 μL
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Catalog No. 50-198-7160 Supplier Bioss Supplier No. BS6257R
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Description

Rabbit Polyclonal Antibody

Stk38,also known as NUCLEAR DBF2-RELATED PROTEIN, contains 1 protein kinase domain that interacts with mob1 and mob2.The homodimeric s100b binds to two molecules of stk38. It is ubiquitously expressed with highest levels observed in peripheral blood leukocytes. Stk38 activated by binding of s100b which releases autoinhibitory n-lobe interactions, enabling atp to bind and the autophosphorylation of ser-281. Thr-444 then undergoes calcium- dependent phosphorylation by an upstream kinase. Interactions between phosphorylated Thr-444 and the n-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of mob1/mobkl1a and mob2/hcca2 to the n-terminal of stk38.

Specifications

Antigen STK38
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene STK38
Gene Accession No. Q15208
Gene Alias 5830476G13Rik; 9530097A09Rik; AA617404; NDR; Ndr Ser/Thr kinase-like protein; NDR1; NDR1 protein kinase; Nuclear Dbf2-related kinase 1; serine/threonine kinase 38; Serine/threonine-protein kinase 38; STK38
Gene Symbols STK38
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human STK38.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11329
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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