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Invitrogen™ STMN4 Polyclonal Antibody
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Catalog No. PIPA5101915
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100 μL
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PIPA5101915 100 μL
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Catalog No. PIPA5101915 Supplier Invitrogen™ Supplier No. PA5101915
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total STMN4.

RB3 (Stathmin-4), encoded by STMN4 gene, is a neuron-specific homologue of the SCG10/stathmin family proteins, possessing a unique N-terminal membrane-associated domain and the stathmin-like domain at the C terminus, which promotes microtubule (MT) catastrophe and/or tubulin sequestering. Stathmin is a ubiquitous cytosolic phosphoprotein, preferentially expressed in the nervous system, and described as a relay integrating diverse intracellular signaling pathways. RB3 is consistently up-regulated in differentiated neuroblastoma cells, and stable expression of transfected RB3 could induce differentiation, suggesting a role of RB3 during neuroblastoma differentiation. Moreover, increased RB3 is a unique response protein in the stathmin-related proteins following optical nerve axotomy and RB3 may be a critical target for neurodegenerative diseases.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STMN4
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene STMN4
Gene Accession No. P63042, P63043, Q9H169
Gene Alias Lagl; R75359; Rb3; stathmin 4; stathmin-4; stathmin-like 4; stathmin-like protein B3; stathmin-like protein RB3; stathmin-like-protein RB3; Stmn4
Gene Symbols STMN4
Host Species Rabbit
Immunogen A synthesized peptide derived from human STMN4(Accession Q9H169), corresponding to amino acid residues M50-A100.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 56471, 79423, 81551
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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