Invitrogen™ STOML1 Polyclonal Antibody

Catalog No.	Quantity
PIPA559953	100 μL

Catalog No. PIPA559953 Supplier Invitrogen™ Supplier No. PA559953

Description

Rabbit Polyclonal Antibody

Immunogen sequence: GPGMVLLLPF IDSFQRVDLR TRAFNVPPCK LASKDGAVLS VGADVQFRIW DPVLSVMTVK DLNTATRMTA QNAMTKALLK RPLREIQMEK LKISDQLLLE INDVTRA Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.

Stomatin-like protein 1 (STOML1) is encoded by the STOML1 gene located on chromosome 17 in humans. It is part of a family of five mammalian genes that encode peripheral membrane proteins involved in modulating ion channel functions. STOML1 is known to interact specifically with members of the acid-sensing ion channel (ASIC) family, influencing their proton sensitivity. These interactions help regulate ion transport and signaling pathways, which are critical for cellular homeostasis. In addition, STOML1 has been studied in the context of oral squamous cell carcinoma (OSCC), where it is often overexpressed along with STOML2, potentially affecting cancer progression. Structurally, STOML1 contains a stomatin domain which is crucial for its role in membrane association and ion channel modulation. Its expression in olfactory sensory neurons (OSNs) is comparatively lower than other family members, but it still contributes to the localization and functional integrity of related proteins in these cells.

Specifications

• Antigen: STOML1
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: STOML1
• Gene Accession No.: Q9UBI4
• Gene Alias: 1810015E19Rik; AI847431; EPB72-like 1; EPB72-like protein 1; hUNC-24; MSTP019; Protein unc-24 homolog; RGD1559463; SLP1; SLP-1; stomatin (EBP72)-like 1; stomatin (EPB72)-like 1; stomatin like 1; stomatin-like 1; stomatin-like protein 1; Stomatin-related protein; STOML1; STORP; UNC24; WPB72
• Gene Symbols: STOML1
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human STOML1. Recombinant protein control fragment (Product #RP-89968).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9399
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG