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Invitrogen™ STOML2 Polyclonal Antibody
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Catalog No. PIPA587867
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PIPA587867 100 μL
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Catalog No. PIPA587867 Supplier Invitrogen™ Supplier No. PA587867
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SSGLPRNTVV LFVPQQEAWV VERMGRFHRI LEPGLNILIP VLDRIRYVQS LKEIVINVPE QSAVTLDNVT LQIDGVLYLR IMDPYKASYG VEDPEYAVTQ LAQTTMRSEL GKLSLDKVFR ERESLNASIV DAINQAADCW GIRCLRYEIK DIHVPPRVKE SMQMQVEAER RKRATVLESE GTRESAINVA EGKKQAQILA SEAEKAEQIN QAAGEASAVL AKAKAKAEAI RILAAALTQH NGDAAASLTV AEQYVSAFSK LAKDSNTILL PSNPGDVTSM VAQAMGVYGA LTKAPVPGTP DSLSSGSSRD VQGTDASLDE ELDRVKMS; Positive Samples: U-87MG, A375, A-549, B-cell, Mouse liver, Mouse kidney, Rat liver, Rat thymus; Cellular Location: Cell membrane, Membrane raft, Mitochondrion inner membrane, Mitochondrion intermembrane space, Peripheral membrane protein.

Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen STOML2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.95 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Stoml2
Gene Accession No. Q4FZT0, Q99JB2, Q9UJZ1
Gene Alias 0610038F01Rik; EPB72-like 2; EPB72-like protein 2; HSPC108; MSLP2; Paraprotein target 7; paratarg-7; Slp2; SLP-2; stomatin (Epb7.2)-like 2; stomatin (EPB72)-like 2; stomatin like 2; stomatin-like 2; stomatin-like protein 2, mitochondrial; Stoml2
Gene Symbols Stoml2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 29-356 of human STOML2 (NP_0384701).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 298203, 30968, 66592
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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