Invitrogen™ Streptococcus pyogenes speB Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5117551

Catalog No. PIPA5117551

Description

This antibody has been tested in direct-ELISA.

Important streptococcal virulence factor which cleaves human fibronectin and degrades vitronectin. Also cleaves human IL1B precursor to form biologically active IL1B. Can induce apoptosis in human monocytes and epithelial cells in vitro, and reduces phagocytic activity in monocytic cells. Thus, may play a role in bacterial colonization, invasion, and inhibition of wound healing.

Specifications

• Antigen: Streptococcus pyogenes speB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Alias: Exotoxin type B; SPP; Streptococcal cysteine proteinase; Streptococcus peptidase A; Streptopain
• Immunogen: Recombinant Streptococcus pyogenes Streptopain protein (146-398aa).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Target Species: Bacteria
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov