Invitrogen™ STX17 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA540127

Catalog No. PA540127

Description

Recommended positive controls: 293T, A431, HeLa, and HepG2 cells. Predicted reactivity: Mouse (89%), Rat (86%), Rhesus Monkey (99%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. STX17 is a SNARE of the autophagosome involved in autophagy through the direct control of autophagosome membrane fusion with the lysosome membrane. STX17 may also play a role in the early secretory pathway where it may maintain the architecture of the endoplasmic reticulum-Golgi intermediate compartment/ERGIC and Golgi and/or regulate transport between the endoplasmic reticulum, the ERGIC and the Golgi. (Uniprot).

Specifications

• Antigen: STX17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: STX17
• Gene Alias: 4833418L03Rik; 6330411F21Rik; 9030425C21Rik; AW048351; Stx17; syntaxin 17; syntaxin-17
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 252853, 55014, 67727
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 1.94 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: P56962, Q9D0I4, Q9Z158
• Gene Symbols: STX17
• Immunogen: Recombinant protein encompassing a sequence within the center region of human STX17.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG