Invitrogen™ Syntaxin 1 Recombinant Rabbit Monoclonal Antibody (7D9V8)

Catalog No.	Quantity
PIMA538015	100 μL

Catalog No. PIMA538015

Supplier: Invitrogen™ MA538015

Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: Mouse spinal cord, Mouse brain, Rat spinal cord Immunogen sequence: MKDRTQELRS AKDSDDEEEV VHVDRDHFMD EFFEQVEEIR GCIEKLSEDV EQVKKQHSAI LAAPNPDEKT KQELEDLTAD IKKTANKVRS KLKAIEQSIE.

Syntaxin 1 is a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: Syntaxin 1
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Recombinant Monoclonal
• Clone: 7D9V8
• Concentration: 0.65 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: Stx1a
• Gene Accession No.: O35526, P32851, Q16623
• Gene Alias: HPC-1; LOW QUALITY PROTEIN: syntaxin-1A; neuron-specific antigen HPC-1; P35-1; P35A; Sap; STX1; Stx1a; STX1B; STX1B1; STX1B2; STXA1; SYN1A; Synaptotagmin-associated 35 kDa protein; syntaxin 1 a; syntaxin 1A; syntaxin 1A (brain); syntaxin 1A (brain)-like; syntaxin-1A; Syntaxin-1B1; Syntaxin-1B2
• Gene Symbols: Stx1a
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Syntaxin (P61266).
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 116470, 20907, 6804
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG