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Invitrogen™ Substance P Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA575165

Catalog No. PIPA575165


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Description

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).

Substance P (SP) is currently thought to be one of the most important neurotransmitters and neurotransmitters in the brain. It is an undecapeptide belonging to the tachykinin family, which consists of excitatory neuropeptides synthesised in neuronal and glial cells of the human central and peripheral nervous system. Substance P, Neurokinin A, Neuropeptide K, and Neuropeptide gamma are all generated by post-translation cleavage of the precursor Protachykinin-1. Substance P forms the major endogenous ligand for Neurokinin 1 Receptor. The pharmacology of Substance P has been associated with a number of neurological and psychiatric disorders, namely nociception, migraine, asthma, nausea, inflammatory bowel syndrome, urinary incontinence, anxiety and depression. It has also been linked to obesity.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Substance P
Polyclonal
Unconjugated
TAC1
4930528L02Rik; C-terminal-flanking peptide; Hs.2563; MGC26719; neurokinin 1; neurokinin 2; neurokinin A; neurokinin alpha; neuromedin L; Neuropeptide gamma; neuropeptide K; NK1; NK-1; NK2; Nka; Nkna; NPK; PPT; Ppt5fl; PPTA; PPT-A; PPTA3; precursor 1; preprotachykinin; preprotachykinin A; protachykinin; protachykinin-1; RAT TAC; RATPPTA3; SP; substance K; Substance P; TAC; Tac1; TAC2; Tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma); tachykinin 1; tachykinin 2; tachykinin precursor 1; tachykinin, precursor 1; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
Rabbit
Antigen affinity chromatography
RUO
21333, 24806, 6863
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
P06767, P20366, P41539
TAC1
Synthetic peptide corresponding to mature of Substance P of human origin.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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