Invitrogen™ SUCLA2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587588

Catalog No. PIPA587588

Description

Immunogen sequence: MAASMFYGRL VAVATLRNHR PRTAQRAAAQ VLGSSGLFNN HGLQVQQQQQ RNLSLHEYMS MELLQEAGVS VPKGYVAKSP DEAYAIAKKL GSKDVVIKAQ VLAGGRGKGT FESGLKGGVK IVFSPEEAKA VSSQMIGKKL FTKQTGEKGR ICNQVLVCER KYPRREYYFA ITMERSFQGP; Positive Samples: 293T, SW480, HeLa, Mouse heart, Mouse liver, Mouse brain, Rat liver; Cellular Location: Mitochondrion.

ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

Specifications

• Antigen: SUCLA2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SUCLA2
• Gene Alias: 4930547K18Rik; A-BETA; A-SCS; ATP-specific succinyl-CoA synthetase subunit beta; ATP-specific succinyl-CoA synthetase, beta subunit; mitochondrial succinyl-CoA ligase [ADP-forming] subunit beta; MTDPS5; renal carcinoma antigen NY-REN-39; RP11-528D24.2; SCSbetaA; SCS-betaA; succinate--CoA ligase (ADP-forming); Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; succinate-CoA ligase ADP-forming beta subunit; succinate-CoA ligase beta subunit; succinate-CoA ligase, ADP-forming, beta subunit; succinate-Coenzyme A ligase, ADP-forming, beta subunit; succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial; succinyl-CoA synthetase beta-A chain; Sucla2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20916, 361071, 8803
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.78 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9P2R7, Q9Z2I9
• Gene Symbols: SUCLA2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human SUCLA2 (NP_0038411).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG