Invitrogen™ SUFU Monoclonal Antibody (T.482.4)

Rabbit Monoclonal Antibody

Supplier:  Invitrogen™ MA514954

Catalog No. PIMA514954

Description

It is not recommended to aliquot this antibody.

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: SUFU
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: SUFU
• Gene Alias: OTTHUMP00000020377; OTTHUMP00000020378; OTTHUMP00000020379; PRO1280; RP11-47A8.1; Su(fu); Sufu; SUFU negative regulator of hedgehog signaling; SUFUH; SUFUXL; suppressor of fused homolog; suppressor of fused homolog (Drosophila); UNQ650/PRO1280
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24069, 51684
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Clone: T.482.4
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5
• Gene Accession No.: Q9UMX1, Q9Z0P7
• Gene Symbols: SUFU
• Immunogen: Synthetic peptide corresponding to residues surrounding Ala340 of human SUFU.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Monkey
• Product Type: Antibody
• Isotype: IgG