Invitrogen™ SUFU Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA582360

Catalog No. PIPA582360

Description

Immunogen sequence: TEELHSAQQW NGQGILELLR TVPIAGGPWL ITDMRRGETI FEIDPHLQER VDKGIETDGS NLSGVSAKCA WDDLSRPPED DEDSRSICIG TQPRRLSGKD TEQIRETLRR GLEINSKPVL PPINPQRQNG LAHDRAPSRK DSLESDSSTA.

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: SUFU
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SUFU
• Gene Alias: OTTHUMP00000020377; OTTHUMP00000020378; OTTHUMP00000020379; PRO1280; RP11-47A8.1; Su(fu); Sufu; SUFU negative regulator of hedgehog signaling; SUFUH; SUFUXL; suppressor of fused homolog; suppressor of fused homolog (Drosophila); UNQ650/PRO1280
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51684
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UMX1
• Gene Symbols: SUFU
• Immunogen: Recombinant protein corresponding to Human SUFU. Recombinant protein control fragment (Product #RP-89321).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov