Invitrogen™ SUFU Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA593201

Catalog No. PIPA593201

Description

Immunogen sequence: PPINPQRQNG LAHDRAPSRK DSLESDSSTA IIPHELIRTR QLESVHLKFN QESGALIPLC LRGRLLHGRH FTYKSITGDM AITFVSTGVE GAFATEEHPY AAHGPWLQIL LTEEFVEKML EDLEDLTSPE EFKLPKEYSW PEKKLKVSIL PDVVFDSPLH; Positive Samples: Mouse testis, Rat kidney; Cellular Location: Cytoplasm, Nucleus.

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: SUFU
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SUFU
• Gene Alias: OTTHUMP00000020377; OTTHUMP00000020378; OTTHUMP00000020379; PRO1280; RP11-47A8.1; Su(fu); Sufu; SUFU negative regulator of hedgehog signaling; SUFUH; SUFUXL; suppressor of fused homolog; suppressor of fused homolog (Drosophila); UNQ650/PRO1280
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24069, 361769, 51684
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1.39 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9UMX1, Q9Z0P7
• Gene Symbols: SUFU
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 325-484 of human SUFU (NP_0572532).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG