Invitrogen™ SULT1A1 Monoclonal Antibody (638708)

Catalog No.	Quantity
PIMA524287	100 μg

Catalog No. PIMA524287 Supplier Invitrogen™ Supplier No. MA524287

Description

Mouse Monoclonal Antibody

In direct ELISAs, 100% cross-reactivity with recombinant human (rh) SULT1A3 and rhSULT1C4 and approximately 10% cross-reactivity with rhSULT1B1 is observed. No cross-reactivity with rhSULT1E1, 2A1, 2B1, or 4A1 is observed. Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of the three groups comprising this superfamily (namely SULT1, SULT2 and SULT3) show selectivity to certain substrate compounds. SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family. Functioning as a homodimer that is expressed in brain, liver, skin and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters and, via this catalytic activity, plays a role in the elimination of a variety of compounds from the body. Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.

Specifications

• Antigen: SULT1A1
• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: 638708
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: SULT1A1
• Gene Accession No.: P50225
• Gene Alias: AI266890; aryl sulfotransferase; Aryl sulfotransferase 1; Aryl sulfotransferase cytosolic 1A phenol-preferring member 3; Aryl sulfotransferase cytosolic, 1A, phenol-preferring, member 3; aryl sulfotransferase IV; arylsulfotransferase ST1A4; ASTIV; CSPS; HAST1/HAST2; MGC131921; MGC5163; Minoxidil sulfotransferase; mSTp1; Mx-ST; OK/SW-cl.88; OTTHUMP00000162568; OTTHUMP00000162569; P PST; P PST 1; Phenol sulfotransferase; Phenol sulfotransferase 1; Phenol sulfotransferase 1a1; phenol/aryl sulfotransferase; phenol-sulfating phenol sulfotransferase 1; P-PST; P-PST 1; PST; PST-1; St1a1; ST1A3; ST1A4; Stm; STP; STP1; sulfokinase; Sulfotransferase 1A1; sulfotransferase family 1A member 1; sulfotransferase family 1A, phenol-preferring, member 1; sulfotransferase family, cytosolic, 1A, phenol preferring; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; sulfotransferase, phenol preferring 1; sulphotransferase family cytosolic 1A phenol-prefering member 1; SULT1A1; Sult1a3; Thermostable phenol sulfotransferase; thermostable phenol sulfotransferase1; ts-PST; TSPST1; Tyrosine-ester sulfotransferase
• Gene Symbols: SULT1A1
• Host Species: Mouse
• Immunogen: E. coli-derived recombinant human Cytosolic Sulfotransferase 1A1/SULT1A1 Glu2-Leu295.
• Purification Method: Protein A/G
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6817
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1