Invitrogen™ SULT1A1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA512247

Catalog No. PIPA512247

Description

This antibody is predicted to react with non-human primate based on sequence homology.

The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens and the regulation of hormones by catalyzing the sulfate conjugation of these substances. Members of the three groups comprising this superfamily (namely SULT1, SULT2 and SULT3) show selectivity to certain substrate compounds. SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family. Functioning as a homodimer that is expressed in brain, liver, skin and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters and, via this catalytic activity, plays a role in the elimination of a variety of compounds from the body. Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.

Specifications

• Antigen: SULT1A1
• Classification: Polyclonal
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P50225, P52840
• Gene Symbols: SULT1A1
• Immunogen: KLH conjugated synthetic peptide between 128-160 amino acids from the central region of human SULT1A1.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: SULT1A1
• Gene Alias: AI266890; aryl sulfotransferase; Aryl sulfotransferase 1; Aryl sulfotransferase cytosolic 1A phenol-preferring member 3; Aryl sulfotransferase cytosolic, 1A, phenol-preferring, member 3; aryl sulfotransferase IV; arylsulfotransferase ST1A4; ASTIV; CSPS; HAST1/HAST2; MGC131921; MGC5163; Minoxidil sulfotransferase; mSTp1; Mx-ST; OK/SW-cl.88; OTTHUMP00000162568; OTTHUMP00000162569; P PST; P PST 1; Phenol sulfotransferase; Phenol sulfotransferase 1; Phenol sulfotransferase 1a1; phenol/aryl sulfotransferase; phenol-sulfating phenol sulfotransferase 1; P-PST; P-PST 1; PST; PST-1; St1a1; ST1A3; ST1A4; Stm; STP; STP1; sulfokinase; Sulfotransferase 1A1; sulfotransferase family 1A member 1; sulfotransferase family 1A, phenol-preferring, member 1; sulfotransferase family, cytosolic, 1A, phenol preferring; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1; sulfotransferase, phenol preferring 1; sulphotransferase family cytosolic 1A phenol-prefering member 1; SULT1A1; Sult1a3; Thermostable phenol sulfotransferase; thermostable phenol sulfotransferase1; ts-PST; TSPST1; Tyrosine-ester sulfotransferase
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 20887, 6817
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid