Invitrogen™ SULT2A1 Recombinant Rabbit Monoclonal Antibody (JG36-18)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA534744

Catalog No. PIMA534744

Description

Positive Control: Mouse kidney lysate, 293T, LOVO, rat adrenal gland tissue, human liver tissue, human liver cancer tissue, human small intestine tissue, mouse liver tissue, HepG2.

SULT1 sulfotransferases exhibit N-sulfating activities of carcinogenic heterocyclic amines, and are selective toward phenols, whereas SULT2 enzymes prefer hydroxysteroids and SULT3 family members are selective for N-substituted aryl and alicyclic compounds. SULT2A1 catalyzes the sulfonation of procarcinogen xenobiotics, hydroxysteroids and bile acids, and is highly expressed in adrenal and liver tissues. SULT2A1 plays a role in hepatic cholesterol homeostasis. SULT2B1 consists of two isoforms, SULT2B1a and SULT2B1b, which are transcribed from the same gene by alternative splicing of their first exons. Both isoforms are highly selective for the sulphation of 3b-hydroxysteroids such as pregnenolone, epiandrosterone, DHEA and androstenediol. SULT2B1b is expressed in prostate, skin, placenta and lung.

Specifications

• Antigen: SULT2A1
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q06520
• Gene Symbols: SULT2A1
• Immunogen: Recombinant protein within Human SULT2A1 aa 140-285.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: JG36-18
• Conjugate: Unconjugated
• Gene: SULT2A1
• Gene Alias: alcohol sulfotransferase; alcohol/hydroxysteroid sulfotransferase; bile salt sulfotransferase; Bile salt sulfotransferase 1; bile-salt sulfotranasferase 2A1; bile-salt sulfotransferase 2A1; Dehydroepiandrosterone sulfotransferase; DHEAS; DHEA-ST; HST; hSTa; Hydroxysteroid sulfotransferase; hydroxysteroid sulfotransferase a; mSTa1; Smp-2; ST; ST2; ST-20; ST2A1; ST2A3; STa; Sta1; Std; Sth1; Sth2; Sulfotransferase 2A1; sulfotransferase family 2A member 1; sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1; sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA) -preferring, member 1; sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1; sulfotransferase hydroxysteroid gene 2; sulfotransferase, DHEA preferring; sulfotransferase, hydroxysteroid preferring 1; sulfotransferase, hydroxysteroid preferring 2; SULT2A1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 6822
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles, store in dark
• Form: Liquid