Invitrogen™ SULT2B1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596780

Catalog No. PIPA596780

Description

Immunogen sequence: MDGPAEPQIP GLWDTYEDDI SEISQKLPGE YFRYKGVPFP VGLYSLESIS LAENTQDVRD DDIFIITYPK SGTTWMIEII CLILKEGDPS WIRSVPIWER APWCETIVGA FSLPDQYSPR LMSSHLPIQI FTKAFFSSKA KVIYMGRNPR DVVVSLYHYS KIAGQLKDPG TPDQFLRDFL KGEVQFGSWF DHIKGWLRMK GKDNFLFITY EELQQDLQGS VERICGFLGR PLGKEALGSV VAHSTFSAMK ANTMSNYTLL PPSLLDHRRG AFLRKGVCGD WKNHFTVAQS EAFDRAYRKQ MRGMPTFPWD EDPEEDGSPD PEPSPEPEPK PSLEPNTSLE REPRPNSSPS PSPGQASETP HPRPS; Positive Samples: BT-474, HT-29, Mouse brain, Rat brain; Cellular Location: Cytoplasm, Microsome, Nucleus.

Cytosolic sulfotransferases (STs or SULTs) catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. Her et al. (1998) identified an EST with homology to ST enzymes. By PCR with human placental and prostate cDNA as template, they isolated 2 alternatively spliced cDNAs, identical throughout most of their sequences, but having different 5-prime ends. The shorter cDNA, SULT2B1a, encodes a protein of 350 amino acids; the longer cDNA, SULT2B1b, encodes a 365-amino acid protein. Genomic PCR analysis revealed that the gene encoding both cDNAs, SULT2B1, contains 7 exons, with 2 alternative first exons being used to generate SULT2B1a and SULT2B1b. Northern blot analysis revealed that the SULT2B1 gene is expressed as a 1.4-kb transcript predominantly in prostate, placenta, and trachea.

Specifications

• Antigen: SULT2B1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SULT2B1
• Gene Alias: AI326997; alcohol sulfotransferase; BB173635; HSST2; Hydroxysteroid sulfotransferase 2; RGD:1308882}; ST2B1; sulfotransferase 2B; sulfotransferase 2B1; Sulfotransferase family 2B member 1; sulfotransferase family cytosolic 2B member 1; sulfotransferase family, cytosolic, 2B, member 1; SULT2B; Sult2b1; sult2b1 {ECO:0000312; SULT2B1a
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 292915, 54200, 6820
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.03 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: O00204, O35400, Q29YR5
• Gene Symbols: SULT2B1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human SULT2B1 (NP_8144441).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG