Invitrogen™ SUMF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589741

Catalog No. PIPA589741

Description

Immunogen sequence: SQEAGTGAGA GSLAGSCGCG TPQRPGAHGS SAAAHRYSRE ANAPGPVPGE RQLAHSKMVP IPAGVFTMGT DDPQIKQDGE APARRVTIDA FYMDAYEVSN TEFEKFVNST GYLTEAEKFG DSFVFEGMLS EQVKTNIQQA VAAAPWWLPV KGANWRHPEG PDSTILHRPD HPVLHVSWND AVAYCTWAGK RLPTEAEWEY SCRGGLHNRL FPWGNKLQPK GQHYANIWQG EFPVTNTGED GFQGTAPVDA FPPNGYGLYN IVGNAWEWTS DWWTVHHSVE ETLNPKGPPS GKDRVKKGGS YMCHRSYCYR YRCAARSQNT PDSSASNLGF RCAADRLPTM D; Positive Samples: HepG2, Jurkat; Cellular Location: Endoplasmic reticulum lumen.

This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: SUMF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SUMF1
• Gene Alias: AA543204; AAPA3037; AI463102; AI851573; C-alpha-formylglycine-generating enzyme 1; Fge; FGly-generating enzyme; Formylglycine-generating enzyme; MGC131853; MGC150436; OTTHUMP00000115300; PSEC0152; sulfatase modifying factor 1; sulfatase-modifying factor 1; SUMF1; UNQ3037; UNQ3037/PRO9852
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 285362
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 3.11 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q8NBK3
• Gene Symbols: SUMF1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 34-374 of human SUMF1 (NP_8774372).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG