Invitrogen™ SUMO-3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA590651

Catalog No. PIPA590651

Description

Immunogen sequence: MSEEKPKEGV KTENDHINLK VAGQDGSVVQ FKIKRHTPLS KLMKAYCERQ GLSMRQIRFR FDGQPINETD TPAQLEMEDE DTIDVFQQQT GG; Positive Samples: U-87MG, LO2, Mouse liver, Mouse kidney, Mouse small intestine, Mouse heart, Rat liver, Rat heart; Cellular Location: Cytoplasm, Nucleus, PML body.

Small ubiquitin-related modifier proteins are members of the ubiquitin-like protein family. SUMO-3 regulates Amyloid beta generation and may be critical in the onset or progression of Alzheimer's disease. SUMO-2/3 forms poly-. SUMO-1, 2, and 3 proteins localize to the nuclear membrane, nuclear bodies, and cytoplasm, respectively. SUMOylation is essential for mammalian cell cycle regulation, SUMO-2/3 localizes to centromeres and condensed chromosomes where binds CENP-E.

Specifications

• Antigen: SUMO-3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SUMO3
• Gene Alias: 2810014B19Rik; D10Ertd345e; small ubiquitin like modifier 3; small ubiquitin-like modifier 3; small ubiquitin-related modifier 3; SMT3 (supressor of mif two, 3) homolog 1; SMT3 homolog 1; SMT3 suppressor of mif two 3 homolog 1; SMT3 suppressor of mif two 3 homolog 3; SMT3 suppressor of mif two 3 homolog 3 (yeast); Smt3A; Smt3B; SMT3H1; SUMO-2; Sumo3; SUMO-3; Ubiquitin-like protein SMT3A; ubiquitin-like protein SMT3B
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20610, 499417, 6612
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.1 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P55854, Q5XIF4, Q9Z172
• Gene Symbols: SUMO3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human SUMO3 (NP_0088672).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG