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Super-DHB suitable for matrix substance for MALDI-MS, ≥99% (HPLC), MilliporeSigma™ Supelco™

$85.80 - $327.00

Specifications

CAS 63542-76-7
Percent Purity ≥99% (sum of DHB and 2-hydroxy-5-methoxybenzoi c acid, HPLC)
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
11-101-4995
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MilliporeSigma Supelco
5086210X10MGF
10 x 10 mg
Each for $241.00
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11-101-4993
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MilliporeSigma Supelco
508621GF
1 g
Each for $85.80
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11-101-4994
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MilliporeSigma Supelco
508625GF
5 g
Each for $327.00
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Description

Description

The “super-DHB” matrix consists of a 9:1 (w/w) mixture of 2,5-DHB and 2-hydroxy-5-methoxybenzoic acid, respectively, since this ratio was found to be the most effective. The beneficial effect of the 2-hydroxy- 5-methoxybenzoic acid additive is attributed to a disorder in the 2,5-DHB crystal lattice resulting in enhanced ion desorption (i.e. ‘softer’ desorption) and reduced internal energy, which in turn results in reduced metastable fragmentation. An increase in sensitivity of up to 2 to 3-fold has been reported for a standard dextran mixture with concomitant enhanced resolution attributed to reduced metastable ion formation. The super-DHB matrix has also been reported to generate enhanced signals from tryptic glycopeptides. The use of super-DHB matrix is reported to reduce the presence of matrix background ions and result in glycan signals exhibiting better signal to noise ratios and higher resolution in the mass spectrum.
Specifications

Specifications

63542-76-7
≥99% (sum of DHB and 2-hydroxy-5-methoxybenzoi c acid, HPLC)
SDS
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