Superoxide Dismutase Polyclonal Antibody, HRP, Rockland™

Catalog No.	Quantity
50-199-1140	100 μL
50-199-1141	25 μL

Catalog No. 50-199-1140 Supplier Rockland Immunochemicals Supplier No. 20043910100

Description

Rabbit Polyclonal Antibody

Store vial at 4°C prior to restoration. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Superoxide Dismutase is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Peroxidase, anti-Rabbit Serum as well as purified and partially purified Superoxide Dismutase [Bovine erythrocytes]. Cross reactivity against Superoxide Dismutase from other tissues and species may occur but have not been specifically determined.

SOD1 (superoxide dismutase) binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

Specifications

• Antigen: Superoxide Dismutase
• Applications: ELISA, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: HRP
• Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
• Gene: SOD1
• Gene Accession No.: P00442
• Gene Alias: ALS; ALS1; B430204E11Rik; BOS_506; Cu(2+)-Zn2+ superoxide dismutase; Cu/Zn superoxide dismutase; Cu/Zn-SOD; CuZn superoxide dismutase; Cu-Zn superoxide dismutase; Cu-Zn superoxide dismutase C-terminal fragment (150AA); CuZnSOD; Cu-Zn-superoxide dismutase; epididymis secretory protein Li 44; HEL-S-44; HGNC:11179; homodimer; hSod1; indophenoloxidase A; Ipo1; Ipo-1; ipoa; sod; SOD, soluble; SOD1; Sod-1; sod1.S; sod1-a; sod1-b; SOD1L1; SODC; Superoxide dismutase [Cu-Zn]; Superoxide dismutase [Cu-Zn] A; superoxide dismutase [Cu-Zn] A-like; Superoxide dismutase 1; superoxide dismutase 1 S homeolog; superoxide dismutase 1, soluble; superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)); superoxide dismutase 1, soluble S homeolog; superoxide dismutase, cystolic; XELAEV_18014289mg; XSODA; xsodb
• Gene Symbols: SOD1
• Host Species: Rabbit
• Immunogen: Superoxide Dismutase [Bovine erythrocytes]
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 281495
• Target Species: Bovine
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Lyophilized