SUR1 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-5550	100 μL

Catalog No. 50-198-5550 Supplier Bioss Supplier No. BS3641R

Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not been fully described.

Specifications

• Antigen: SUR1
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: ABCC8
• Gene Accession No.: Q09428
• Gene Alias: ABC36; Abcc8; AM60008PU-N; ATP binding cassette subfamily C member 8; ATP-binding cassette sub-family C member 8; ATP-binding cassette transporter sub-family C member 8; ATP-binding cassette, subfamily C (CFTR/MRP), member 8; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; BOS_14519; D930031B21Rik; HHF1; HI; HRINS; MRP8; PH SUR1; PHHI; sulfonylurea receptor; sulfonylurea receptor (hyperinsulinemia); Sulfonylurea receptor 1; sulfonylurea receptor subunit 1; sulphonylurea receptor 1; SUR; Sur1; SUR1 protein; SUR1delta2; TNDM2
• Gene Symbols: ABCC8
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human SUR1.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6833
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG