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  6. Thermo Scientific™ SurePac™ Protein RP MDi™ HPLC Columns

Thermo Scientific™ SurePac™ Protein RP MDi™ HPLC Columns

Catalog No. 43722022132
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Diameter (Metric):
2.1 mm
300 μm
Length (Metric):
20 mm
50 mm
100 mm
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Catalog No. Diameter (Metric) Length (Metric)
43-722-022132 2.1 mm 20 mm
43-722-052132 2.1 mm 50 mm
43-722-102132 2.1 mm 100 mm
43-722-050332 300 μm 50 mm
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Catalog No. 43-722-022132 Supplier Thermo Scientific™ Supplier No. 43722022132
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Description

SurePac Protein RP MDi is a bioinert reversed-phase column engineered for robust HPLC and LC-MS analysis of intact proteins, mAbs and ADCs. It minimizes unspecific interactions with the column hardware, improves recovery, and delivers reproducible, high-resolution separations for sensitive therapeutic proteins workflows.

Thermo Scientific™ SurePac™ Protein RP MDi™ HPLC columns deliver high-resolution, reproducible separations for monoclonal antibodies, antibody subunits, and ADCs across development and QC workflows. Built on monodisperse, supermacroporous polymeric particle technology with bio-inert hardware, they provide stable performance under elevated temperatures used in LC-MS, enabling consistent peak shape, reliable resolution, and durable operation for scalable protein analysis.

  • Designed for reversed-phase protein separations
  • Engineered for intact proteins, mAbs and ADCs, delivering reliable retention and selectivity across a wide range of molecular weights.
  • Bioinert, metal-free flow path
  • Optimized for LC-MS protein workflows
  • Fully compatible with MS-friendly mobile phases, enabling sensitive and reproducible detection of intact proteins and peptide maps.
  • Robust stationary phase for high-temperature operation
  • Maintains stable performance under elevated temperatures and high organic conditions, supporting fast gradients and durable methods.
  • Excellent peak shape and resolution
  • Delivers sharp, symmetrical peaks and effective separation of protein variants, isoforms, and closely related species.
  • Reproducible performance across columns and batches
  • Tight manufacturing controls ensure consistent results and smooth method transfer between instruments and laboratories.
  • Suitable for development and routine analysis
  • Supports method development, characterization, and QC workflows, reducing the need for multiple column chemistries.
  • Compatible with UHPLC and HPLC systems
TRUSTED_SUSTAINABILITY

Specifications

Column Format Analytical
Diameter (Metric) 2.1 mm
Flow Rate 0.2 to 1 mL/min.
Length (Metric) 20 mm
Max. Pressure 6500 psi (448 bar)
Particle Size 2.5 μm
pH 2 to 12
Pore Size Proprietary supermacroporous
Temperature 5°C to 90°C
Stationary Phase Poly-DVB
Packing Material Polymeric
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