Invitrogen™ SUV39H1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529470

Catalog No. PIPA529470

Description

Recommended positive controls: 293T, A431, HeLa, HepG2, H1299, Raji, Mouse brain. Predicted reactivity: Mouse (98%), Rat (98%), Xenopus laevis (90%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: SUV39H1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SUV39H1
• Gene Alias: AI852103; AL022883; DXHXS7466e; H3-K9-HMTase 1; Histone H3-K9 methyltransferase 1; histone-lysine N-methyltransferase SUV39H1; histone-lysine N-methyltransferase, H3 lysine-9 specific 1; KMT1A; Lysine N-methyltransferase 1A; MG44; mIS6; Position-effect variegation 3-9 homolog; RGD1565028; Su(var)3-9 homolog 1; suppressor of variegation 3-9 homolog 1; suppressor of variegation 3-9 homolog 1 (Drosophila); SUV39H; Suv39h histone methyltransferase; SUV39H1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20937, 6839
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 0.52 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: O43463, O54864
• Gene Symbols: SUV39H1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 179 and 412 of Human SUV39H1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Monkey
• Product Type: Antibody
• Isotype: IgG