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Invitrogen™ SUV39H2 Recombinant Rabbit Monoclonal Antibody (6L2D9)
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Catalog No. PIMA542835
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100 μL
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PIMA542835 100 μL
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Catalog No. PIMA542835 Supplier Invitrogen™ Supplier No. MA542835
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Rabbit Recombinant Monoclonal Antibody

Positive test controls include: HeLa, PC-3. Immunogen sequence: ESDEFTVDAA RYGNVSHFVN HSCDPNLQVF NVFIDNLDTR LPRIALFSTR TINAGEELTF DYQMKGSGDI SSDSIDHSPA KKRVRTVCKC GAVTCRGYLN.

The murine gene Suv39h2 encodes an H3 histone methyltransferase (HMTase) 59% identical in sequence to mouse Suv39h1. During embryogenesis, both proteins overlap in tissue expression, yet Suv39h2 transcripts are restricted to the testes in adult animals. Immunolocalization of the Suv39h2 protein during spermatogenesis indicates enrichment at the heterochromatin from the leptotene to the round spermatid stage. Moreover, Suv39h2 specifically accumulates with chromatin of the sex chromosomes, which undergo transcriptional silencing during the first meiotic prophase. Suv39h2 HMTase may also organize meiotic heterochromatin with the potential for epigenetic imprint to the male germline.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SUV39H2
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 6L2D9
Concentration 1.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SUV39H2
Gene Accession No. Q9H5I1
Gene Alias 4930507K23Rik; AA536750; D030054H19Rik; D2Ertd544e; FLJ23414; H3 K9 HMTase 2; H3-K9-HMTase 2; Histone H3-K9 methyltransferase 2; histone-lysine N-methyltransferase SUV39H2; KMT1; KMT1B; lysine N-methyltransferase 1B; RP11-2K17.2; Su; Su(var)3-9 homolog 2; suppressor of variegation 3-9 homolog 2; suppressor of variegation 3-9 homolog 2 (Drosophila); Suv39h histone methyltransferase; Suv39h2
Gene Symbols SUV39H2
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 311-410 of human KMT1B / SUV39H2 (Q9H5I1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79723
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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