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Invitrogen™ SUV420H1 Polyclonal Antibody
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Catalog No. PIPA566611
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100 μL
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PIPA566611 100 μL
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Catalog No. PIPA566611 Supplier Invitrogen™ Supplier No. PA566611
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DQGEHSGTVGV PVSYTDCAPS PVGCSVVTSD SFKTKDSFRT AKSKKKRRIT RYDAQLILEN NSGIPKLTLR Highest antigen sequence identity to the following orthologs - mouse 86%, rat 87%.

Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SUV420H1
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene KMT5B
Gene Accession No. Q4FZB7
Gene Alias [histone H4]-lysine20 N-methyltransferase KMT5B; [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B; AA117471; C630029K18Rik; CGI85; CGI-85; histone-lysine N-methyltransferase KMT5B; histone-lysine N-methyltransferase SUV420H1; Kmt5b; lysine (K)-specific methyltransferase 5B; lysine methyltransferase 5B; lysine N-methyltransferase 5B; Lysine-specific methyltransferase 5B; MGC118906; MGC118909; MGC21161; MGC703; si:dkey-12e7.2; Su(var)4-20 homolog 1; suppressor of variegation 4-20 homolog 1; suppressor of variegation 4-20 homolog 1 (Drosophila); suppressor of variegation 4-20 protein-like 1; SUV420; SUV420H1; suv4-20h1; Unknown (protein for MGC:137299); wu:fb97g06; wu:fi57g03; zgc:103527
Gene Symbols KMT5B
Host Species Rabbit
Immunogen Recombinant Human SUV420H1. Recombinant protein control fragment (Product #RP-107271).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51111
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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