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Invitrogen™ SUV420H2 Chimeric Recombinant Rabbit Monoclonal Antibody (RAB-C409)
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Catalog No. PIMA548341
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200 μg
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PIMA548341 200 μg
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Catalog No. PIMA548341 Supplier Invitrogen™ Supplier No. MA548341
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Rabbit Recombinant Monoclonal Antibody

Specificity: This antibody recognizes KMT5C (Histone-lysine N-methyltransferase KMT5C). It binds to a folded domain, amino acids 2-248. KMT5C is a histone methyltransferase that regulates transcription and maintenance of genome integrity.

SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
TRUSTED_SUSTAINABILITY

Specifications

Antigen SUV420H2 Chimeric
Applications ChIP Assay, ELISA, Flow Cytometry, Immunoprecipitation, Immunocytochemistry
Classification Recombinant Monoclonal
Clone RAB-C409
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene KMT5C
Gene Accession No. Q86Y97
Gene Alias BC024816; Histone-lysine N-methyltransferase KMT5C; histone-lysine N-methyltransferase SUV420H2; KMT5C; lysine (K)-specific methyltransferase 5C; lysine methyltransferase 5C; lysine N-methyltransferase 5C; Lysine-specific methyltransferase 5C; PP7130; Su(var)4-20 homolog 2; suppressor of variegation 4-20 homolog 2; suppressor of variegation 4-20 homolog 2 (Drosophila); SUV420H2; suv4-20h2
Gene Symbols KMT5C
Host Species Rabbit
Immunogen This antibody was obtained by recombinant antibody (rAb) phage display recognizing SUV420H2 protein under non-denaturing conditions.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84787
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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