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Invitrogen™ SUV420H2 Polyclonal Antibody
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Catalog No. PIPA5109891
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100 μL
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PIPA5109891 100 μL
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Catalog No. PIPA5109891 Supplier Invitrogen™ Supplier No. PA5109891
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Rabbit Polyclonal Antibody

Immunogen sequence: FLPESGFTIL PCTRYSMETN GAKIVSTRAW KKNEKLELLV GCIAELREAD EGLLRAGEND FSIMYSTRKR SAQLWLGPAA FINHDCKPNC KFVPADGNAA C.

SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).
TRUSTED_SUSTAINABILITY

Specifications

Antigen SUV420H2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 2.66 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene KMT5C
Gene Accession No. Q6Q783, Q86Y97
Gene Alias BC024816; Histone-lysine N-methyltransferase KMT5C; histone-lysine N-methyltransferase SUV420H2; KMT5C; lysine (K)-specific methyltransferase 5C; lysine methyltransferase 5C; lysine N-methyltransferase 5C; Lysine-specific methyltransferase 5C; PP7130; Su(var)4-20 homolog 2; suppressor of variegation 4-20 homolog 2; suppressor of variegation 4-20 homolog 2 (Drosophila); SUV420H2; suv4-20h2
Gene Symbols KMT5C
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 232811, 84787
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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