Invitrogen™ SUV420H2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109891

Catalog No. PIPA5109891

Description

Immunogen sequence: FLPESGFTIL PCTRYSMETN GAKIVSTRAW KKNEKLELLV GCIAELREAD EGLLRAGEND FSIMYSTRKR SAQLWLGPAA FINHDCKPNC KFVPADGNAA C.

SUV420H2 is a histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. The protein mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2).

Specifications

• Antigen: SUV420H2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: KMT5C
• Gene Alias: BC024816; Histone-lysine N-methyltransferase KMT5C; histone-lysine N-methyltransferase SUV420H2; KMT5C; lysine (K)-specific methyltransferase 5C; lysine methyltransferase 5C; lysine N-methyltransferase 5C; Lysine-specific methyltransferase 5C; PP7130; Su(var)4-20 homolog 2; suppressor of variegation 4-20 homolog 2; suppressor of variegation 4-20 homolog 2 (Drosophila); SUV420H2; suv4-20h2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 232811, 84787
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.64 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q6Q783, Q86Y97
• Gene Symbols: KMT5C
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human KMT5C (NP_116090.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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